EVENT DETAILS AND ABSTRACT

Title: Regulation of MAP kinase activity revealed by mathematical modeling and experimental analysis
Speaker: Tim Elston
Speaker Info: University of North Carolina, Chapel Hill
Brief Description:
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Abstract:

Signaling pathways that allow cells to respond appropriately to different external stimuli often share common components. Therefore an important question in cell signaling is how pathway specificity is achieved. In yeast,two developmental pathways, mating and invasive growth, are regulated by the same MAP kinase cascade. After providing an introduction to these signaling pathways, I will discuss an integrated research approach that combines mathematical modeling with experimental investigations to uncover the mechanism that leads to pathway specificity at the MAP kinase level.