EVENT DETAILS AND ABSTRACT

Title: Model Genetic Networks and Principles of Robust Transcription Control
Speaker: Boris Shraiman
Speaker Info: Bell Labs
Brief Description:
Special Note: More current information may be available at Plan-it Purple
Abstract:

Normal function and development of cells and organisms depends on the timely expression of appropriate genes. This process is controlled by the interactions of transcription factor proteins with regulatory segments of DNA which form links in the genetic network governing cell function. One of the remarkable properties of this system is its stability with respect to mutations. What are the principles underlying robust transcription control and governing the organization of such networks? The talk will address this question on a basis of a model network, then discuss avenues for comparing theoretical predictions with experimental data for the relatively simple example of E.coli.